申请日期 | 2024-11-17 | 申请号 | CA2507893 |
公开(公告)号 | CA2507893A1 | 公开(公告)日 | 2004-11-04 |
公开国别 | CA | 申请人省市代码 | 全国 |
申请人 | STAV ORGANICKE CHEMIE A BIOCHEMIE AKADEMIE VED CESKE REPUBLIKY | ||
简介 | The invention provides a synthetic method of (purin-6-yl)amino acids which a re useful as medicaments of anticancer, anti-virus agents and so on or their intermediates. Methyl (R, S)-3-[4-(9-benzylpurin-6-yl) phenyl]-2-[ (t- butoxycarbonyl) amino] propanoate is produced by making 9-benzyl-6-iodopurin e react with methyl (R, S)-2-[ (t-butoxycarbonyl) amino]-3-[4- (trimethylstananyl) phenyl] propionate in the presence of Pd2dba3, triphenylarsine and copper iodide. |
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