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NOVEL METHOD OF HIGHLY SENSITIVE NUCLEIC ACID ANALYSIS 发明申请

2022-07-31 4700 431K 0

专利信息

申请日期 2024-11-18 申请号 EP03744032
公开(公告)号 EP1491629A1 公开(公告)日 2004-12-29
公开国别 EP 申请人省市代码 全国
申请人 Matsumoto Kazuko; Mitsubishi Rayon Co Ltd
简介 It is intended to provide a method of highly sensitively analyzing SNPs. More specifically, it is intended to provide an SNP analysis method whereby a large amount of SNPs can be quickly analyzed using a DNA sample in a trace amount. An SNP analysis method by the invader method with the use of a FRET probe having a luminescent dye and a quencher characterized by using, as the luminescent dye in the FRET probe, a rare earth fluorescent complex label made of a rare earth element such as europium or terbium. A composition for controlling fluorescent luminescence which comprises a combination of a specific rare earth fluorescent complex label with a specific fluorescent quencher. A highly sensitive labeling probe characterized by using a rare earth fluorescent complex label as a luminescent dye and a fluorescent quencher label as a quencher in a highly sensitive labeling probe such as a FRET probe and an SNP analysis kit containing the same.


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