| 简介 |
PROBLEM TO BE SOLVED : To provide a method for efficiently producing an organic compound of which halogen atoms are substituted with nucleophilic agent by allowing the halogen compound having the halogen atom that is connected to the carbon atoms forming the σ bond with four atoms in the molecule to react with a nucleophilic agent.
SOLUTION : In the presence of a compound represented by general formula (1) (wherein Z- is an anion represented by the form that proton is removed from an inorganic acid or an active hydrogen compound; R is a 1-10C hydrocarbon group or Rs may bond each other to form a ring together with N atom), a compound represented by general formula (2) : MQa [wherein M is an alkali metal atom, an alkaline earth metal atom or a rare earth metal atom; Q is a residual group after proton(s) are removed from an inorganic acid or an active hydrogen bearing compound; and a is an integer of 1-3] and an organic halogen compound are allowed to react each other whereby at least one of halogen atom is substituted with Q and a Q-bearing organic compound is obtained. |
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