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APPARATUS AND METHOD FOR MULTIPLEXED ROTATING IMAGING BIOASSAYS 发明申请

2022-06-06 1190 4475K 0

专利信息

申请日期 2025-02-24 申请号 WOCN17100841
公开(公告)号 WO2018045978A1 公开(公告)日 2018-03-15
公开国别 WO 申请人省市代码 全国
申请人 VERSITECH LIMITED
简介 Systems and method for versatile multiplexed spinning/rotating bioassays are provided. This bioassay platform can take the advantage of the high-speed spinning motion, which naturally provides on-the-fly cellular imaging at the rate that cannot be reached by the conventional cameras or laser-scanning techniques, but ultrafast imaging modalities. More importantly, the functionalized solid substrates derived from the disk substrate can be compatible with adherent cell culture as well as biochemically-specific cell-capture, which can now be assayed with ultrafast imaging modalities at an ultra-high-speed line-scan rate of >10 MHz. Large-format spinning high-throughput imaging assay could thus be a potent tool for scaling both the assay throughput as well as content/multiplexity as demanded in many applications, e.g. drug discovery, and rare cancer cell screening.


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